Services heading north out of Preston are currently held after a person was hit by a train.
All lines between Preston and Lancaster, a key route connecting the north of England to the Midlands and the South, are blocked as a result of the incident.
Delays of up to 120 minutes are expected, according to Avanti West Coast.
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London North Eastern Railway, Northern, Scotrail and CrossCountry are accepting tickets via any reasonable route until further notice.
Blog Preston has contacted British Transport Police for more information.
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