A clinical trial in Preston is aiming to find an antibody combination that can prevent Covid-19.Advertisement
Panthera Biopartners, based at Issa Medical Centre in Deepdale, has begun dosing volunteers in the Phase III PROVENT trial, which will evaluate AstraZeneca’s long-acting antibody combination, AZD7442.
The double-blind, placebo-controlled trial includes adult volunteers who have no history of Covid-19 and have an increased risk of infection or who are more likely to be exposed to the virus.
The aim is to evaluate the safety and effectiveness of a combination of two long-acting monoclonal antibodies – man-made versions of naturally occurring human antibodies of the immune system – in preventing Covid-19 infection.
The ‘antibody combination’ differs from a vaccine as it provides antibodies, rather than prompting the body’s immune system to make them.
The treatment is aimed at helping those people with a compromised immune system, who cannot be vaccinated, the vaccine hesitant and those who are unlikely to respond to a vaccination.
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The trial, which will run for a year, is taking place alongside others at Panthera sites in North Manchester and North London.
Strict protocols are in place to minimise the risk to both volunteers and staff, and ensure the trial can continue throughout the pandemic.
In the event of any volunteers developing Covid-19 symptoms, Panthera says it will provide support to the patient and ensure the study can continue with affected individuals safely isolated.
Stuart Young, CEO of Panthera, said: “We are delighted that we have been chosen to enrol volunteers in this critical study.
“We have taken great care in making sure our sites are as safe as possible for both volunteers and staff so that clinical trials can continue.
“This is vital in ensuring there are new medications available to prevent and treat not only Covid-19, but the many other conditions that afflict so many people.”
Panthera is also currently conducting clinical trials for migraines and osteoarthritis.
To find out more, contact the recruitment team at Panthera’s Preston site on 03300 553327 or firstname.lastname@example.org
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What do you think of the trial taking place in Preston? Would you volunteer? Let us know in the comments.