A main road in Penwortham was closed in both directions due to a crash.
Golden Way, the A582, was shut by South Ribble Police.
Police were called around 1.35pm on Thursday (13 June) to a collision between a car and a pedestrian.
A police spokeswoman said the pedestrian involved had suffered leg injuries.
The North West Ambulance Service confirmed a man was taken to Royal Preston Hospital with serious injuries.
Golden Way was closed in both directions from the roundabout at Booths to the A59.
Read more: Work on the A59 in Penwortham for new bypass to cause disruption
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