Traffic at Broughton crossroads was brought to a standstill once more during Monday evening.
Four cars were involved in the collision at the recently revamped junction.
The incident took place shortly after 5.30pm on Monday (18 December).
There are not believed to be any serious injuries.
Read more: Changes planned for the Broughton crossroads
Whittingham Lane meets what was the A6 with the priority changed for drivers coming from East and West, rather than North and South.
Numerous crashes have been reported at the crossroads since the change in priorities and the opening of the Broughton Bypass.
Read more: Broughton Bypass named in honour of Preston war hero
Owner of the Chameleon restaurant and bar, which faces onto the crossroads, said it was only a matter of time before someone was seriously hurt due to the road layout changes.
Broughton resident Dale Green has written to Wyre and Preston North MP about the junction.
He said: “I drove home tonight and passed the crossroads minutes after the accident there.
“During my commute, this is the second I have seen but aware there have been several more since the flawed changes imposed by LCC.
“What pressure can be put on LCC before there is fatality of a motorist or pedestrian?
“This fiasco is costing millions in insurance payout, affecting peoples lives, emergency services time, NHS time and resources and for what? How are these costs accounted for?
“The changes are supposed to be for the better and make things safer but they are not. LCC have had to put temporary signs there as well but all they did when first put there was block the view out!
“The lights just need to turned back on, fitted with sensors so they change to suit the traffic flow, simple.
“It only matter of time before there is fatality and it can so easily be avoided.
“I and many people I know feel the same so what can we do to get this sorted out?”