Mariners Way was closed on Saturday (28 October) lunchtime following a crash.
Two cars were involved in the collision which took place shortly after 12.30pm.
Emergency services closed off the road near the exit from the Morrisons garage.
A black saloon car and small white car were involved.
Buses were diverted from the Docks area in Ashton-on-Ribble while the crash was cleared.
Read more: Police car involved in crash at Preston Docks
The road re-opened around an hour later.
No one is thought to have been hurt in the crash.