Police had closed two lanes of the M55 near Preston following an overturned vehicle.
A van and trailer has flipped over just past where the slip road joins the motorway at Broughton (Junction 1).
The M55 now has all lanes reopened following the crash at 7.20am on Tuesday (20 June) heading towards Blackpool.
Police said the driver had received minor injuries.
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The motorway is expected to be cleared around 8.30am but delays are expected as the morning rush hour builds.