Shopkeepers fear that the current dip in sales could mean the death of the high street as the north south divide grows ever bigger.
Figures released by the Local Data Company show the shop vacancy gap between the north and the south rose by 2.5 per cent in the last six months.
In Preston there are currently 100 empty shops with the worst areas being Church Street with 21 empty shops and 15 on Friargate.
Nearly 800 towns were surveyed nationally with an average of 14.5 per cent of shops being empty in town centres, compared to 12 per cent in 2009.
David Halewood, owner of Halewood and Sons Booksellers on Friargate says the trend is likely to continue.
âItâs the way retail is changing,â he said. âThe future is pretty grim. Some will linger on longer than others.
âIt will not be a high street as we know it in the future. People want the immediacy. No-one wants to go from one grumpy shopkeeper who doesnât know what they want to one who doesnât have it.
However Preston has not been hit as hard as other Lancashire towns with 30 per cent of all shops in Morecambe standing empty and is now the worst medium-sized town in the country.
Nearby Blackpool also has over a quarter of its shop units standing idle.
However deputy council leader, Eric Fazackerley, sees a brighter future for Prestonâs shops.
He said: âWe are seeing quite a lot of interest from large organisations. When you get the big developments coming in it attracts the smaller ones.â
Mr Fazackerley highlighted the planned Tithebarn and Central Business District (CBD) developments as ways to reinvigorate the city.
âThe sooner we get them the better because Preston is a growth spot. The main difficulty is traffic but the county council are going to get that sorted out including plans for a new bus station.
âThere is a big interest in the CBD from the private sector, including a new hotel. But what we are trying to get is substantial office accommodation, you canât get that in Preston at the moment.â
Another area which has lost out in the past few years is the Victorian arcade on Fishergate, which currently has four out of its 10 shopping units empty.
Peter Whittaker, the manager of Rohan Outdoor Clothing, hopes for more competition to boost trade.
âPeople said when Milletâs closed âyou must be delightedâ but I welcome the competition, itâs excellent,â he said.
âIt gives the customer a greater selection of products; otherwise they may as well go to somewhere like Manchester. Itâs good for the customer and itâs good for business.
âBut itâs definitely getting harder for shops and itâs at a depressing stage, which is evident by the number of departures.â